3rd generation glp-1 vs GLP-2 vs GLP-3: The Science Behind Modern Metabolic Peptides Transforming obesity: The advancement of

J Med Chem 61:20522061 Sandler U, Devary O, Braitbard O, Ohana J, Kass G, Rubinstein AM, Friedman ZY, Devary Y (2010) NEROFEa novel human hormone-peptide with anti-cancer activity

Nitric oxide (NO) signaling cascade The generation of nitric oxide (NO) catalyzed by endothelial nitric oxide synthase (eNOS) plays a critical role in protecting the vascular endothelium from oxidative and inflammatory insults (27)

He Y, Li S, Zhang W, Dai W, Cui T, Wang G, et al

Heres a breakdown of the most common GLP-1 brands, what they contain, and what you might expect to pay, including lower-cost compounded alternatives: Wegovy (semaglutide) FDA approved for weight loss Estimated retail price: $1,350/month Ozempic (semaglutide) FDA approved for type 2 diabetes

Tirzepatide is similar to semaglutide, but it is actually a dual agonist and works by two mechanisms instead of one